Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 36 Reviews
8.2
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Iron (as iron bisglycinate chelate†)
25 mg
139%
Top Medical Research Studies
8
We explored how iron influences food poisoning, particularly in the context of campylobacteriosis, a common foodborne illness. Our focus was on the effects of deferoxamine (DESF), an iron-chelating compound, when administered orally to mice before they were infected.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
Read More
Most Useful Reviews
9
No constipation noted
51 people found this helpful
This is the best iron! I battled anaemia and dizziness for ages and suffered from severe constipation with other medications. A doctor recommended this easily digestible iron from Solgar, which has been my salvation! No side effects or constipation, just one capsule daily with food. Within a month, my hemoglobin rose above average and my ferritin improved as well. I continue to take it.
Read More
9
Great absorption noted
12 people found this helpful
This is a great iron supplement! It’s in a good absorbable chelated form which rarely causes side effects. Although my deficit isn’t large, it did help. I added vitamin C for better absorption and took it after meals. I experienced no constipation and just observed a change in stool colour. After eight weeks, my ferritin and hemoglobin levels improved.
Read More
9
No nausea experienced
11 people found this helpful
Nausea-free iron supplement. When I was examined at the hospital, my ferritin was 12 and I suffered from severe iron deficiency. I purchased an iron supplement but vomited immediately after taking it. Other iron supplements caused rough stomach and severe nausea, but this one is the only one I can take without feeling sick. I consumed about half the bottle with no side effects. While chelated iron has a risk of cancer, this non-chelated iron can be taken safely.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
We explored how iron influences food poisoning, particularly in the context of campylobacteriosis, a common foodborne illness. Our focus was on the effects of deferoxamine (DESF), an iron-chelating compound, when administered orally to mice before they were infected.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
Read More
User Reviews
USERS' SCORE
Good
Based on 36 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
No constipation noted
51 people found this helpful
This is the best iron! I battled anaemia and dizziness for ages and suffered from severe constipation with other medications. A doctor recommended this easily digestible iron from Solgar, which has been my salvation! No side effects or constipation, just one capsule daily with food. Within a month, my hemoglobin rose above average and my ferritin improved as well. I continue to take it.
Read More
9
Great absorption noted
12 people found this helpful
This is a great iron supplement! It’s in a good absorbable chelated form which rarely causes side effects. Although my deficit isn’t large, it did help. I added vitamin C for better absorption and took it after meals. I experienced no constipation and just observed a change in stool colour. After eight weeks, my ferritin and hemoglobin levels improved.
Read More
9
No nausea experienced
11 people found this helpful
Nausea-free iron supplement. When I was examined at the hospital, my ferritin was 12 and I suffered from severe iron deficiency. I purchased an iron supplement but vomited immediately after taking it. Other iron supplements caused rough stomach and severe nausea, but this one is the only one I can take without feeling sick. I consumed about half the bottle with no side effects. While chelated iron has a risk of cancer, this non-chelated iron can be taken safely.
Read More
9
Stopped hair loss
7 people found this helpful
The best!!! Rapidly replenished my iron deficiency and increased ferritin. After COVID, my hair fell out badly, resulting in noticeable bald patches. I checked my levels – ferritin was at 18, low B12, and high homocysteine. I took various supplements including Vitamin C with meals, and introduced iron after 1.5 months, which boosted ferritin from 18 to 63 over 49 days. I also made dietary changes, adding iron-rich foods. After several months, with my levels rising, my hair loss ceased. Always remember to take iron with an acidic drink for better absorption!
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8
Effective in raising ferritin
6 people found this helpful
This supplement increased my ferritin from 15 to 37 µg/l and iron levels from 16 to 21 µmol/l within two months. I took two capsules daily with food, consistently using vitamin C to enhance absorption, though I couldn't tolerate higher doses. I’m extremely satisfied with the results compared to a previous pharmacy version that only improved ferritin by one unit.
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Frequently Asked Questions
7.5
No digestive issues
2 people found this helpful
I believe this will help! My ferritin is low, and I felt terrible. I took this iron, strictly followed all instructions, and after three weeks, my hemoglobin rose from 107 to 115. My condition improved, I lost weight, and experienced better digestion without constipation or bloating. I will continue to take it, believing it will raise my hemoglobin further!
7.5
Excellent mild form
3 people found this helpful
This iron is an excellent choice—gentle on the stomach without causing constipation. My ferritin rose from 15 to 90 within two months of taking one tablet daily with vitamin C. It’s crucial to avoid calcium-rich foods and beverages like coffee and tea right before or after taking iron, as they hinder absorption. This form can be taken on an empty stomach without issues.
8
Effective in raising ferritin
6 people found this helpful
This supplement increased my ferritin from 15 to 37 µg/l and iron levels from 16 to 21 µmol/l within two months. I took two capsules daily with food, consistently using vitamin C to enhance absorption, though I couldn't tolerate higher doses. I’m extremely satisfied with the results compared to a previous pharmacy version that only improved ferritin by one unit.
9
Replenished iron stores
1 people found this helpful
After testing my ferritin and haemoglobin earlier this year, I found low results: haemoglobin at 118 and ferritin at 4. I chose this iron from Solgar, as Russian ferrum upset my stomach. After consuming 180 capsules over six months, my tests improved: ferritin at 54, normal serum iron, and haemoglobin at 125. I take it daily with food and vitamin C, defying the belief that dietary supplements are ineffective.
9
No constipation noted
51 people found this helpful
This is the best iron! I battled anaemia and dizziness for ages and suffered from severe constipation with other medications. A doctor recommended this easily digestible iron from Solgar, which has been my salvation! No side effects or constipation, just one capsule daily with food. Within a month, my hemoglobin rose above average and my ferritin improved as well. I continue to take it.
9
No nausea experienced
11 people found this helpful
Nausea-free iron supplement. When I was examined at the hospital, my ferritin was 12 and I suffered from severe iron deficiency. I purchased an iron supplement but vomited immediately after taking it. Other iron supplements caused rough stomach and severe nausea, but this one is the only one I can take without feeling sick. I consumed about half the bottle with no side effects. While chelated iron has a risk of cancer, this non-chelated iron can be taken safely.
10
Significant ferritin increase
3 people found this helpful
After being advised to take iron with vitamin C, my ferritin levels improved from 7 to 48 after two months. I consumed three iron capsules and one vitamin C daily while avoiding coffee and tea during meals. This method yielded excellent results, as my serum iron levels are now normal. I highly recommend this product for anyone needing to boost ferritin!
9
Promotes iron absorption
2 people found this helpful
This product effectively raises iron levels without causing constipation or side effects. I suggest separating the intake of zinc and calcium to optimise absorption, taking iron in the morning and the others later in the day. Dairy, tea, coffee, and eggs can interfere with iron uptake; hence, timing is crucial. This approach works wonders for improving iron levels!
9
Iron supplement success
4 people found this helpful
I've used iron supplements with apple cider vinegar to great effect. Now, "constipation from iron" is a thing of the past, and my ferritin and hemoglobin levels have normalised. I strategically take iron during menstruation to offset significant losses. Avoiding foods that block iron absorption has proven effective. With the proper approach, this product has excelled!
8
We explored how iron influences food poisoning, particularly in the context of campylobacteriosis, a common foodborne illness. Our focus was on the effects of deferoxamine (DESF), an iron-chelating compound, when administered orally to mice before they were infected.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
References
- Bereswill S, Mousavi S, Weschka D, Buczkowski A, Schmidt S, et al. Iron Deprivation by Oral Deferoxamine Application Alleviates Acute Campylobacteriosis in a Clinical Murine Infection Model. Biomolecules. 2022;13. doi:10.3390/biom13010071
